Whether or not to have children is often a major decision, but the decision can be difficult where the parents know or suspect that one of them may carry a faulty gene, which could cause a health problem for the child they may have. The decision to have a baby may lead to a number of further decisions to be made in regards to the possible genetic testing of the embryo/foetus during the pregnancy.

These tests have certain limitations, and although a faulty gene is detected in the embryo, it is not always possible to predict with certainty what the likelihood is of that foetus surviving or what kind of quality of life a child would have.